Welcome to Mysooru News

mysore latest news

UoM initiative! Former VC Prof K S Rangappa led scientists devise rapid Covid-19 detection kit

3 min read

The unique feature of the kit is that a barcode strip that is connected with an app is provided. As soon as the barcode is scanned, patient health status (positive/negative) is updated in the server which enables the governing agency to monitor COVID-positive cases rapidly

Mysuru: The University of Mysore in association with Lorven Biologics Pvt Ltd, Hyderabad have designed ‘Covi Direct’ a new rapid COVID-19 detection kit.

Announcing this to media, former VC of University of Mysore Prof K S Rangappa, who led the team of scientists in devisingtthe kit said “COVID-19 disease is the deadliest human ailment that affected the globe. We are dependent on rapid detection method and RT-PCR for the diagnosis of COVID-19. During the early days of COVID-19 (i.e., in the month of April 2020), we decided to
design a kit that can detect the COVID infection rapidly. Some big companies
developed and released rapid detection kits immediately. So, we decided to develop a
new kit that can overcome the limitations associated with the existing strategies.”

We are aware of the fact that we are dependent on rapid detection methods and RT-PCR for the diagnosis of COVID-19. Generally, the existing rapid detection methods offer accuracy of detection from 60-90%. Therefore, RT-PCR was widely used as a confirmatory test during the first wave of COVID-19. Unfortunately, up to 40 per cent of COVID-19-positive patients were diagnosed as COVID-19 negative (false negative) in RT-PCR during the second wave.

Therefore, it is the need of an hour to have a new kit that can detect all the mutated variants of COVID-19 rapidly. We are hoping that the kit will be able to detect the COVID-19 virus in the subsequent waves, said Rangappa.

Any person suspected of COVID-19 symptoms who can use this kit to test the COVID-19 virus in body fluids including sputum, nasal secretions, and saliva.
Nucleoplasmid protein of COVID-19 was cloned and expressed in a suitable system.
Thereafter, antibodies are raised against nucleoplasmid protein. Gold nanoparticle-based ICG strips were developed using purified antibodies for detection of the COVID-19 virus from suspected samples.

The unique feature of the kit is that we are providing a barcode strip that is connected with an app. As soon as the barcode is scanned, patient health status (positive/negative) is updated in the server which enables the governing agency to monitor the COVID-positive cases rapidly.

The advance technologies related
to molecular biology, nanotechnology, and artificial intelligence were used to develop
this kit.

The kit is developed with a motto on par with “Make in India” and “AatmaNirbhar Bharat Abhiyaan” which are our Prime minister’s dream projects. Since the kit is developed by a State University (government institution), is expected to have low cost.

We will send the kit to the Indian Council for Medical Research (ICMR), Government
of India for emergency approval. We are attempting to formulate a drug for COVID-19 in association with the Indian
Institute of chemical technology (IICT, Hyderabad) and central drug research institute (CDRI, Lucknow). We have got good results with the drug design so far and hopefully, we will have good news soon, said Rangappa.

Prof G Hemantha Kumar, Vice-Chancellor, University of Mysore immensely supported the project throughout the process of kit development.

The University of Mysore team headed by Rangappa includes Dr S Chandra Nayak, Coordinator, University of Mysore, Mysore, and Dr C D Mohan, Assistant Professor, Department of Studies in Molecular Biology, University of Mysore, Mysore.

Dr Venkataramana, Director, Lorven Biologics Pvt Ltd Hyderabad was instrumental in the preparation of this kit. He provided the scientific and logistical support for the design of this kit. It is the unique contribution of the University of Mysore to our country in a fight against the pandemic, said Rangappa.

– Team Mysoorunews

Mysooru News

Share this